A System-Theoretic Epistemology of Genomics
نویسنده
چکیده
The text is organised as follows. In the first part, there are six main propositions, preceded by a definition. Referring mainly to the philosophy of Arthur Schopenhauer, the first proposition provides the foundation for a phenomenological perspective of science and describes the certainty of uncertainty in any scientific enquiry; following the bad news, the second proposition recovers objective knowledge within the realm of the world of experience. The third proposition formalises the scientific method in form of Robert Rosen’s modelling relation and introduces a system theory based on sets and relations. Proposition four describes entailment structures that are a basic tool of science. Proposition five describes Schopenhauer’s ‘differentiation’ as the basic mode of operation for human minds and the last proposition draws some conclusions from differentiation. I briefly mention some personal conclusions on the consequences of the approach and provide examples for the conceptual framework presented. The examples are used to introduce a novel fuzzy relational model of geneexpression and function. The approach follows directly from the considerations in the main part of the text and is intended as a step towards a system theory of genomics. Merging Rosen’s modelling relation and factor space theory, the paper establishes formal relationships of the approach to rough set theory, which has been successful in data mining applications, and evidence theory used in uncertainty modelling.
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تاریخ انتشار 2000